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Who Should Consider Semaglutide GLP-1? Semaglutide GLP-1 is generally recommended for individuals with type 2 diabetes who have not achieved adequate blood sugar control with other medications such as metformin, or for
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However, these pharmacologic benefits are tempered by important trade-offs, including gastrointestinal side effects, treatment cost, and loss of lean mass, which may have long-term functional implications if not counteracted by concurrent resistance exercise (17–19)
