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Underwood et al., 2011), residues E292 ECL2 , D293 ECL2 , E294 ECL2 , W297 ECL2 , R299 ECL2 , N300 ECL2 , N302 ECL2 , and N304 ECL2 all play a role in GLP-1 action (Y305 5.35b is involved too—see TM5 below)
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