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The Science - In a groundbreaking discovery, scientists have found that the pancreas can naturally produce GLP-1, the hormone targeted by popular medications like Ozempic. GLP-1 (glucagon-like peptide-1) plays a crucial role

In Vivo Assessment of Drug Interactions Effects of Sitagliptin on Other Drugs In clinical studies, sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, digoxin, warfarin, or an oral contraceptive (ethinyl estradiol and norethindrone) (Table 4), providing in vivo evidence of a low propensity for causing drug interactions with substrates of CYP3A4, CYP2C8, CYP2C9, P-gp, and organic cationic transporter (OCT)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Queiroz V.N.F., Falsarella P.M., Chaves R.C.F., et al

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