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10.4 FLOW Trial: Extended Analysis and Practical Implications The Decision to Stop Early FLOW was stopped early by the independent data monitoring committee at the second planned interim analysis, when the pre-specified efficacy boundary for the primary composite endpoint was crossed
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However, sucrose has a few shortcomings, such as its high caloric value, ability to induce hyperglycemic reactions, and diabetes mellitus (Grassi et al., 2021)
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