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( 10.1111/dom.12932) [DOI] [PMC free article] [PubMed] [Google Scholar] 22.A heart disease study of semaglutide in patients with type 2 diabetes (SOUL)

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The primary drawbacks of pharmacological glucagon therapy for metabolic syndrome, aside from hyperglycemia, are hemodynamic properties that include effects of increased heart rate and cardiac contractility [138]