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Preserving muscle mass is crucial for strength and mobility
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This repression was hypothesized to be important for stem cell maintenance since RNAi-mediated knockdown of mpk-1 increased the number of mitotic germ cells, while promoting MPK-1 activity by a Ras gain-of-function mutation let-60(n1046) decreased the number of mitotic germ cells (Lee et al., 2006)
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