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This is to make sure that you’re being safely evaluated and monitored in terms of your medical history and concerns, and that you’re aware of any contraindications or side effects of the medication (which are headache, fatigue, and nausea and other GI issues)

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CB0313.1 was administered daily by oral gavage to leptin db/db mice for 5 weeks starting from 3 weeks of age, and to HF diabetic mice induced by high fat diet (HFD) plus streptozotocin (STZ) in C57BL/6J mice for 13 weeks starting from 4 weeks of age