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In parallel, emerging data from male reproductive studies suggest that GLP-1RAs may positively influence the hypothalamic-pituitary–testicular axis, improve testicular function, and enhance spermatogenesis, particularly in obese men

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2 To put the rapid increase in utilization of these medications in perspective, GLP-1 agonists are forecasted to have sales of approximately $50 billion in 2024, the largest annual sales figure ever for a class of drugs, and expected to surpass $100 billion in annual sales by 2029

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