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The patch pipette solution contained (in mM): 140 Cs-glutamate, 10 NaCl, 1 MgCl 2 , 0.2 EGTA, 2 MgATP, and 5 HEPES adjusted to pH 7.4 with CsOH
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We are also encouraged that the consensus highlights fatigue and cognitive domains as core components of the PBC patient experience, and recognises the importance of robust, standardised tools for assessing clinically meaningful change
