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Estrogen Exposure and Adipose-Driven Hormonal Modulation Because adipose tissue produces estrogen via aromatase, reductions in visceral fat can lower peripheral estrogen levels in some individuals
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Small intestinal lipid infusion lowers hepatic glucose production via a vagal gut–brain–liver axis that is dependent upon CCK-1R signaling, although recent evidence suggests that GLP-1R signaling also contributes to the effect 130,194
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