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Clinical red flags that suggest cardiac origin include: sudden onset of severe symptoms, radiation to typical cardiac distribution areas, associated autonomic symptoms (sweating, pallor), exertional provocation, and risk factors such as prior cardiovascular disease, long-standing diabetes, hypertension, dyslipidemia, or family history of premature coronary disease
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6.4 Frequency of Review There is no formal consensus on monitoring intervals specific to GLP-1 therapy
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