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TIRZEPATIDE Mechanism of action of tirzepatide GIP = glucose-dependent insulinotropic polypeptide; GLP-1 = glucagon-like peptide 1; LDL = low-density lipoprotein; HR = heart rate.

A spokesperson for the company said: “While Novo Nordisk acknowledges that all licensed prescribers have the choice to prescribe treatments outside of their intended purpose, or approved parameters of use, Novo Nordisk does not endorse this in any way.” A Department of Health and Social Care spokesperson said the government was taking a multifaceted approach to tackling obesity

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Patient outcomes — in the limited published case series and clinic-level data — are broadly similar to brand outcomes