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Discussion In this trial, semaglutide improved glycemic control, with lower insulin requirements, in adults with T1D when used with AID
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Preclinical studies have also revealed that dual agonists of GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR) have synergistic anti-inflammatory and neuroprotective effects, suggesting the potential advantages of multitargeting strategies (Yuan et al., 2024)
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