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Subsequent superiority trials with liraglutide, subcutaneous semaglutide, albiglutide, dulaglutide and efpeglenatide established that sustained GLP-1 receptor activation can reduce atherosclerotic events in populations with T2DM and high cardiovascular risk (1–3, 14, 15)

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Functional studies highlight major microbiota components’ roles in the gut-brain axis [191,192,193,194]