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fda drug safety communication semaglutide naion 2025 Novo Nordisk's Wegovy® pill (oral 25 mg, once daily) has just been approved by the US as the first oral GLP‑1 receptor agonist for long‑term weight management and CV risk Health & Beauty in Pack Size:14 Tablets Vitamin B12 Deficency

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Key Findings Summary Weight Loss: Semaglutide 2.4 mg weekly produces mean weight loss of 14.9-17.4% across the STEP trial program, with approximately one-third of patients achieving ≥20% weight loss

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But recently, GLP-1s have gained mainstream attention and adoption due to their applications for weight loss—originally highlighted as a “side effect.” Those findings led to widespread media coverage and celebrity endorsements, helping fuel a rapid increase in interest and prescribing of GLP-1 medications