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GLP-1 Drug Use Surges: 11% of Americans on Weight Loss Medications as Obesity Rate Drops - One-Time Gain Impact

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GLP-1 receptor agonists should be considered when patients experience significant weight regain with BMI ≥27 kg/m² with obesity-related comorbidities or BMI ≥30 kg/m², lifestyle modifications have been insufficient, no anatomical complications require surgical revision, and patients are willing to engage in long-term pharmacotherapy