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This MI-induced GLP-1 secretion was cardioprotective, as mice treated with a GLP-1R inhibitor had worse left ventricular (LV) function after LAD artery ligation
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While semaglutide activates only the GLP-1 receptor and tirzepatide targets both GLP-1 and GIP receptors, retatrutide activates all three metabolic hormone receptors: GLP-1, GIP, and glucagon
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