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(2026) propose a compelling perspective: creatine supplementation may be a practical, evidence-based strategy to prevent muscle atrophy in patients using incretin-based therapies.🟢 The problem: Incretin-based pharmacotherapies reduce caloric intake by 16–39%, and the resulting energy deficit can compromise fat-free mass, metabolic rate, and functional capacity.🟢 Creatine is well-established for enhancing muscle mass, strength, and cellular energetics across diverse populations
