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By week 40, the majority of patients in the tirzepatide group had significantly lower systolic and diastolic blood pressure than those in the placebo group (a difference of 6.1 to 12.6 mmHg and 1.7 to 2.1 mmHg, respectively) [8-10,25], and they also showed lower triglycerides and low-density lipoprotein cholesterol (LDL-C), and higher high-density lipoprotein cholesterol (HDL-C) as compared to other agents [65]
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