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DPP-4 protease is constructed by five subsites, S 2 subsite buildup of several amino acids like Arg125, Arg358, Arg669, Phe357, Glu205, and Glu206, shown in the figure in magenta color, whereas the catalytic triad is composed of Ser630, Asp708, Asn710, His740 amino acid residues highlighted by red color

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doi: 10.1210/jc.2010-2724

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