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If reconstituted material must be stored, aliquoting into small single-use portions and freezing at minus twenty degrees Celsius or lower can extend stability, though this approach requires validation to ensure maintained potency through the freeze-thaw process
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This trial enrolled over 9,600 patients with type 2 diabetes and high cardiovascular risk, either established cardiovascular disease or chronic kidney disease, and compared oral semaglutide 14mg daily against placebo over approximately four years
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