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It has an amino acid substitution at position 8 (Aib instead of Ala) to prevent DPP-4 cleavage, and a C-18 fatty acyl chain with a spacer attached at Lysine 26, which gives it strong albumin binding (even more than liraglutide’s C-16) ( [114] ) ( [48] )
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For many people on GLP-1s, inhaled THC feels more consistent, while edibles require extra caution and patience
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