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272 participants randomized. Baseline Mean body weight : 108.7 kg Mean weight loss at week 26: −8.6% to −12.6% orforglipron dose cohorts −2.0% in the placebo group. ➡️Daily oral orforglipron, a nonpeptide

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Supplementary material The Supplementary Material for this article can be found online at: References 1 AgusA.PlanchaisJ.SokolH