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Evio’s study found: Across GLP-1 agonists, a single medication had the worst range of clinical outcomes, with a higher incidence of biliary disease, more progression to bariatric surgery, and the lowest adherence and persistence rates CV events did not differ among the GLP-1 agonists studied Total cost of care was driven by the cost differences between the medications themselves, not hospitalizations or other HCRU In addition to educating patients and providers about study findings, Evio recommends that health plans consider evaluating their benefit design based on study results – while still considering all existing research conducted to date

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Moreover, the C-terminal serine of the peptide was replaced by cysteine via site-directed mutagenesis performed with polyethylene glycol