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13 No RCTs have primarily tested the effects of GLP-1 RAs on HF hard outcomes and/or mortality in patients with HFpEF or HF with reduced ejection fraction (HFrEF)
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Head-to-head comparison The SURPASS-2 trial compared tirzepatide directly against semaglutide 1.0mg (not the higher 2.4mg weight management dose)
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