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On average, participants saw their daily step counts drop from 5,047 down to 4,487 steps per day, while their high-value moderate-to-vigorous physical activity (MVPA) fell from 28 down to just 22 minutes per day
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Within this region, GLP-1R is expressed in POMC neurons (37, 76, 77) and in a recently described population of thyrotropin-releasing hormone–expressing (TRH-expressing) neurons that send inhibitory projections to AgRP neurons (78)
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