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Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that extends the activity of the body's natural incretin hormones, whereas GLP-1 agonists directly stimulate GLP-1 receptors throughout the body

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Trulicity, is expected to read out in Q4/2024, before SURMOUNT-MMO, and thus could provide important, earlier outcomes data in support of tirzepatide even for its obesity indication 9