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That brings us to: Building a GLP-1 portfolio Core drug developers | 88% Unsurprisingly, the majority of our investment must be allocated to the core drug developers

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GLP-1RA corrects this imbalance through the following mechanisms: β cell function protection and regeneration: GLP-1RA not only promotes insulin synthesis through cAMP-PKA pathway, but also realizes the increase of β cell number and functional recovery by inhibiting β cell apoptosis and promoting α cell to β cell transdifferentiation (for example, GCGR monoclonal antibody combined with GLP-1RA treatment can triple the number of β cells in type 1 diabetes mice)