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Fenugreek (Trigonella foenum-graecum), a common ingredient in South Asian and Middle Eastern cooking, contains soluble fiber and 4-hydroxyisoleucine, which may augment glucose-dependent insulin secretion and slow carbohydrate absorption
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This work further highlights how physiologically relevant in vitro systems are becoming a mechanistic backbone for predicting oral bioavailability, improving translational relevance, and supporting the development of next-generation therapeutics
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